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Ascorbate uptake enables tubular mitophagy to prevent septic AKI by PINK1-PARK2 axis

Then, an increased epithelial permeability to ions is translated as an increase in conductance

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26 HanadaN.TakahataT.ZhouQ.YeX.SunR.ItohJ.et al (2012)

For example, NETs contribute to thrombosis and activate macrophage NLRP3 inflammasome, while EVs can increase endothelial permeability and stimulate the production of inflammatory mediators

Currently, the challenge is to standardize the protocols for the generation of brain organoids, to automate and scale the processes (from generation to the analysis of large amounts of data), and to efficiently translate results to patients