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Relevant to the previously mentioned synergistic effect of GHRP-2 and endogenous GHRH is the fact that GHRP-2 amplifies the naturally occurring pulsatile GH secretion that becomes diminished as the relative concentrations of GHRH decline with age (Figure 8)
Research into next generation peptides is already exploring triple-agonist compounds like retatrutide , which activates GLP-1, GIP, and glucagon receptors simultaneously
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National Library of Medicine (US), MedlinePlus
