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MSC-like cells isolated from peripheral blood of osteoporotic patients with intervention with bisphosphonates showed significantly increased expression levels of the osteoblast marker gene Runt-associated transcription factor 2 (RUNX2) , BMP-2 and bone turnover markers C-terminal telopeptide (CTX), pre-collagen type 1 N-terminal pro-peptide (P1NP) and bone alkaline phosphatase (bALP) levels were significantly reduced (Dalle Carbonare et al., 2017

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P., Huber, A

The peptide's preclinical data is compelling, but the gap between a rat esophageal healing study and a human therapeutic application is enormous

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