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FXR-deficient mice are resistant to obesity induced by a high-fat diet, and transferring their microbiota to germ-free wild-type mice reduces obesity and improves glucose tolerance, indicating that the gut microbiota promotes weight gain and hepatic steatosis in an FXR-dependent manner (Parsus et al., 2017)

Defensins are cysteine rich endogenous antimicrobial peptides which consist of to approximately 5% of total granulocyte proteins, following infection their levels in systemic circulation increases, defensins have a significant effect on a wide spectrum of microorganisms[1719] and beyond that they also act as immunologic mediators[20]

Unprocessed immunoblots

The control diet group focused on portion control whereas the MIND diet group increased consumption of foods found in the MIND diet

Vasconcelos SM, Goulart MO, Silva MA, et al

A 3D-Bioprinted dual growth factor-releasing intervertebral disc scaffold induces nucleus pulposus and annulus fibrosus reconstruction