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TGF2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells

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elegans does not synthesize cyclopropane lipids, suggesting that F13D12.9 could instead be involved in MFA biosynthesis 41,43,47

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In contrast, the long-term negative effects resulting from chronic consumption of EDs include increased blood pressure, deleterious effects on the heart function, with the risk of increased arrhythmogenesis, induction of migraines, development of dyspeptic disorders of the upper gastrointestinal tract, diarrhea resulting from accelerated intestinal motility, liver damage, and renal tubular dysfunction, associated with the risk of developing acute kidney injury [40]