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PMID: 27167460

doi: 10.3390/sports11090177, 44

This includes employing mitochondrial-targeted peptides and exploring gene therapies aimed at correcting defective mitophagy (e.g., via the PINK1-Parkin pathway) or normalizing imbalanced mitochondrial dynamics (Wang et al., 2025a

Independent of the cause, the observation of decreased tryptophan levels in PD may be relevant for the choice of adjuvant treatments, as reduced plasma and serum levels of tryptophan have been linked with depression by multiple studies 58,59

The non-availability of proper diagnostic tools, the lack of awareness among the patients about future complications, and the condition being cloaked without symptoms in the beginning makes it more of a put off problem

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