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Clinical trials paint a reassuring safety picture, though we need more data on long-term use

A growing body of evidence has identified the role of sphingolipids, particularly ceramide, in the pathogenesis of both microvascular and macrovascular diabetic complications

AO/PI staining and Annexin-V FITC assays confirmed apoptotic cell death, with cell cycle arrest at the sub-G1 phase

doi: 10.1080/07352680091139231 97 StrodtktterI.PadmasreeK.DinakarC.SpethB.NiaziP

Calcineurin expression, activation, and function in cardiac pressure-overload hypertrophy

Invading macrophages and activated microglia cells accumulate VLCFA probably originating from the phagocytosed myelin