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ATTAIN-2 (NCT05872620) This trial evaluated orforglipron in adults with obesity or overweight who also had type 2 diabetes, a critically important subpopulation given the high co-prevalence of these conditions

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Cobalamins circulate bound to serum proteins called transcobalamins (TC) and haptocorrins

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How to Obtain Issues in the Ontario Health Technology Assessment Series All reports in the Ontario Health Technology Assessment Series are freely available in PDF format at the following URL: The Ontario Health Technology Assessment Series is currently indexed in MEDLINE/PubMed, Excerpta Medica/Embase, and the Centre for Reviews and Dissemination database

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One reason: Changes in stomach acid can be part of aging, and you need hydrochloric acid in your stomach to absorb B12

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