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This dose selection was informed by the Phase 2 observation that the 36 mg and 45 mg doses showed only modestly different efficacy but the 45 mg dose carried higher rates of gastrointestinal adverse events
Do not double the dose to make up for a missed one
If vitamin B12 treatment failed to alleviate the patients symptoms, the panelists agreed that doctors should consider alternative conditions that may explain the symptoms and should reevaluate the appropriateness of the dose of B12 therapy
After the injection, the B12 is absorbed into the bloodstream and transported throughout the body
Keep the dry powder cold, sealed, and out of light
