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Liposome-based drug delivery systems rely on the intactness of the skin barrier to effectively transport drugs to the target site within the skin or to allow systemic absorption

BCAAs induce significant changes in genes and proteins associated with ferroptosis in neurons and increase lipid ROS levels, causing ferroptosis in primary cultured cortical neurons and ischemic tissue

W.OBrienJ.et al (2010)

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Further, manipulation of crosslinks may be applied to a variety of tissue engineering techniques that use collagen-based biomaterials to modulate mechanical properties and failure mechanisms