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Description
annuum in HR
Front Oncol 12:1015200
( I ) Oxygen consumption rate of HepG2 hepatocytes measured using the Agilent Seahorse XFe24 Analyzer under sequential treatment with oligomycin (Oligo), carbonyl cyanide p -trifluoromethoxyphenylhydrazone (FCCP), and rotenone plus antimycin A (Rot+AA)
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Enzymatic Mechanism CYP-catalyzed oxygenations are NADPH-dependent and involve the scission of dioxygen with one oxygen atom reduced to water and the other incorporated into the substrate
This uncoupling process releases the energy of the electrochemical proton gradient as heat
