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The affinity of the PV3 wild type was 51.0 nM, whereas the mutants K87pAcF, C23pAcF, S85pAcF and N77pAcF showed a significant increase in binding affinity
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In summary, endothelial cells ferroptosis plays an important role in promoting atherosclerosis, and inhibition of ferroptosis by improving antioxidant metabolism may be a new target for protecting atherosclerosis

Gafter-GviliARozen-ZviBVidalLLeiboviciLVansteenkisteJGafterUet al

doi: 10.1186/s11671-016-1517-3 219
