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Likewise, remarkable safety (i.e., LD50 higher than 2000 mg/kg through oral or intravenous route in mice) confirmed no adverse effect in toxicology studies (none of the animals died)

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doi:10.1038/npre.2009.2988.1

Since its introduction, 5-Amino-1MQ has become a valuable research tool within metabolic science, obesity research, and cellular physiology investigations aimed at understanding the role of NNMT in human biology