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N-acetylcysteine as add-on to antidepressant medication in therapy refractory major depressive disorder patients with increased inflammatory activity: Study protocol of a double-blind randomized placebo-controlled trial

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*Correspondence: Jianan Huang [email protected] Liu [email protected] Liu [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Plant Development and EvoDevo, a section of the journal Frontiers in Plant Science Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Yuen MF, Heo J, Jang JW, Yoon JH, Kweon YO, Park SJ, Tami Y, You S, Yates P, Tao Y, Cremer J, Campbell F, Elston R, Theodore D, Paff M, Bennett CF, Kwoh TJ

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These findings provide the first evidence that BBR mitigates CKD through the gut-kidney axis, highlighting its considerable potential as a therapeutic agent for CKD management (Liu et al., 2016)