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Non-cystic fibrosis bronchiectasis generally presents with dilated airways, excess mucus secretion, persistent cough, and frequent respiratory infections in similar patterns as other muco-obstructive pulmonary diseases (Ramsey et al., 2020

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Cardiac TFAM mRNA levels were increased (2-fold) in rosiglitazone-treated C57BL/6 mice, but combined treatment with rosiglitazone and WY-14643 prevented this increase (Figure 3A)