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Although uterine expression levels of estrogen receptor , G protein-coupled estrogen receptor, and steroid synthase were upregulated in the high-dose group, the decreased expression of connexin 43 and alkaline phosphatase as well as the increased expression of insulin-like growth factor-binding protein three and monoamine oxidase were consistent with decreased estrogen signaling and lower uterine weights

Furthermore, we consider precautionary B12 treatment to be an appropriate and advisable response to such symptoms, due to the number of positive experience reports as well as the fact that blood measurements and other test factors are often misleading in this area