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Description
Dworkin SI, Guerin GF, Co C, Goeders NE, Smith JE
The mutant T60 CARD8 could not bind to NLRP3 and prevent its oligomerization, undermining the NLRP3 inflammasome (94)
The GS-TNB is subsequently reduced by glutathione reductase and -nicotinamide adenine dinucleotide phosphate (NADPH), releasing a second TMB molecule and recycling the GSH
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Any visible glow usually reflects improved antioxidant status and calmer inflammation
These compounds play an important role in preventing oxidative stress caused by the endogenous formation of hydrogen peroxide (H 2 O 2 ) by aerobic metabolism
