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The supplement may also interact with certain chemotherapy drugs, so cancer patients should always discuss supplementation with their oncologist before use

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Quality Assessment The methodological qualities of the included RCTs were assessed according to Cochrane Collaboration's tool described in Handbook version 5.1.0 [10]

Insulin sensitivity pilot study (Ruggenenti): A pilot study in nondiabetic subjects at increased cardiovascular risk with insulin resistance found that 2 g/day of oral ALCAR for 6 months improved insulin-mediated glucose disposal (measured by euglycemic hyperinsulinemic clamp) alongside reductions in blood pressure [5][21]