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Description
This method appears to be especially suited for use in populations with a high prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency (18)

Inflammatory cytokines secreted in the inflammatory area, such as granulocyte-macrophage colony stimulating factor (GM-CSF), TNF-, IL-1, and interferon, can activate HIF-1 to inhibit neutrophil apoptosis (62, 63)
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Clustering of integral membrane proteins of the human erythrocyte membrane stimulates autologous IgG binding, complement deposition, and phagocytosis

Adaptations in the local microenvironment lead to a reprogramming of energy metabolism to accommodate these changes

Extracellular vesicles (exosomes and ectosomes) play key roles in the pathology of brain diseases
