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Description
History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy

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Reuptake inhibitor of serotonin, noradrenaline, and dopamine Tesofensine increases monoaminergic transmission by inhibiting the neuronal uptake of serotonin, dopamine, and noradrenaline, thus causing appetite suppression

The short answer: the ideal needle size for a B12 injection depends on the injection method

Common Side Effects Associated with Tesofensine In clinical trials, Tesofensine has generally been well-tolerated, with most side effects reported as mild to moderate

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