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Moreover, compounds associated with nucleotide metabolism, such as 5-methylthioadenosine, xanthine, and hypoxanthine, were also elevated, alongside phenylalanine metabolism intermediates like phenylacetaldehyde and folate metabolism-related substances including 4-aminobenzoic acid

In particular, USP22 raised GSH content and reduced the occurrence of ferroptosis in cardiomyocytes by activating the Sirt1-p53/SLC7A11 axis [252]
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10.21037/atm-22-3298 36 MobarraN.ShanakiM.EhteramH.NasiriH.SahmaniM.SaeidiM.et al (2016)

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