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Suppressing the Wnt-CTNNB--catenin axis will upregulate P62, which is associated with the blockade of autophagy

When cellular serine levels decrease, it activates one of the main effectors of the mTOR transcription factor, activating transcription factor 4 (ATF4), which then promotes the expression of serine synthesis pathway (SSP) enzymes to bring the serine level back to normal [71]

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GSH deficiency is associated with age, a major risk factor for SARS-CoV-2 infections outcome (Grigoletto Fernandes et al., 2020

P-EIF2 , phosphorylated subunit of eukaryotic initiation factor 2