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Cheignon C, Tomas M, Bonnefont-Rousselot D et al (2018) Oxidative stress and the amyloid beta peptide in Alzheimers disease
One possible explanation for the absence of a clear G4 signature is intercalation of the small molecule into the RNA, as planar cationic aromatics are known to partially intercalate into non-G4 RNAs 40,41

Activation and nuclear translocation of the primary transcription factor Nrf2 promote the expression of these enzymes, providing robust protection against oxidative damage [44]

It is extensively studied in molecular and regenerative research for its role in cellular signalling, tissue organisation, and biological repair pathways

doi: 10.1074/jbc.RA118.004280, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 104.Rasoolijazi H, Joghataie MT, Roghani M, Nobakht M

This finding is consistent with established research on the mechanism of action of acrylamide, which highlights its role in inducing oxidative stress and biochemical perturbations in rat brains (Yousef & El-Demerdash, 2006)
