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demonstrated that in T cells with deficient mitochondrial transcription factor A genes ( Tfam ), mtDNA content decreased, leading to mitochondrial dysfunction

[DOI] [PubMed] [Google Scholar] 237.Calandre E.P., Rico-Villademoros F

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Furthermore, as Al toxicity induce water stress, these osmolyte function as osmoprotectants by reducing intracellular water potential, regulating turgor dynamics and stabilizing proteins and membrane integrity, thereby promoting Al tolerance (Ejaz et al., 2020)

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