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The progress of hydrolysis at pH 6 was monitored by gel permeation chromatography which showed partial degradation of orthoester and resulted into sharp decrease in molecular weights and low molecular weight oligomers were observed with 2 h (Table 2)

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Pringsheim T, Jette N, Frolkis A, Steeves TD
10.1016/j.ygeno.2020.02.007 Genomics 109 HannaC.KelseyG

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Moreover, in a sepsis model, Dex could exert neuroprotective effects by inhibiting the proptosis of astrocytes [6]
