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Silymarin and Inflammation: Food for Thoughts

Our goal is to move beyond the hype and facilitate a critical evaluation of the current scientific landscape, empowering informed decision-making in practice

Jiang Z, Wang T, Yuan S, Wang M, Qi W, Su R, He Z

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Every time athletes exert themselves, the body converts increased oxygen to energy, releasing free radicals that steal electrons from healthy cells and tissues

Glutathione peroxidase 4 (GPX4) as a selenoperoxidase is a key upstream regulator of ferroptosis which plays two simultaneous roles, one in converting reduced GSH to glutathione disulfide (GSSG) and the other is to inhibit ferroptosis by reducing phospholipid hydroperoxides (PLOOHs) to the corresponding alcohols (PLOHs), thereby preventing the accumulation of lipid peroxides (Jiang et al., 2021)