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DSPE-PEG-GSH is added after preparation of the liposomes by incubation at 25 0 C up to 6O 0 C for 2 up to 24 hours (depending on the transition temperature of the lipid mixture and the temperature sensitivity of the agent)

doi: 10.1074/jbc.M109.016766

Given these limitations, there is a growing need to explore alternative treatments, such as phytochemicals and herbal extracts

This is tremendously interesting, but not super relevant to understanding the article

Finally, combining vectors with biocompatible scaffolds or hydrogels may extend intra-articular retention and promote localized expression

Genetic predisposition is seen in certain cases
