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Jong CJ, Sandal P and Schaffer SW, et al
These physical symptoms occur because B12 deficiency damages nerve pathways throughout your entire body, not just your brain

Curcumin inhibited IL-6-induced proliferation, migration, and invasiveness of human small cell lung cancer (SCLC) cells by reducing JAK/STAT3 phosphorylation (i.e., activation) and downstream genes coding for cyclin B1, survivin, Bcl-X L , MMPs, intercellular adhesion molecule 1 (ICAM-1), and vascular endothelial growth factor (VEGF) (30)

Guzman et al

Gluten free diet and nutrient deficiencies: a review
So I Think what the good side of that being part of the culture is