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doi: 10.1016/j.biopsych.2008.04.022

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reported that exogenous H 2 S modulates the NRF2/GPX4/GSH pathway by enhancing Syvn1-Keap1 interactions, which in turn mitigates ferroptosis and mitochondrial apoptosis linked to oxidative stress and antioxidant pathways in diabetic mouse hearts [110]

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For example, one ingredient may provide an energy substrate to improve physical capacity directly, while another nutrient may decrease fatigue through a separate pathway (19, 20)

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In liver cancer, caraglipzin (CANA) can reduce aerobic glycolysis in HCC by targeting pyruvate kinase M2 (PKM2)

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