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PubMed, Purves, Dale, et al

Dihydroorotate dehydrogenase (DHODH), a mitochondrial enzyme involved in ferroptosis regulation [13], presents an alternative pathway for inducing ferroptotic cell death, particularly in GPX4-low expressing glioblastoma cells

In vitro experiments demonstrated that N4Py-S-S-FA elicited good selectivity toward FR-expressing KB and IGROV-1 tumor cells and is similarly cytotoxic as the parent iron complex of the ligand N4Py

Nchoutpouen E, Talipouo A, Djiappi-Tchamen B, Djamouko-Djonkam L, Kopya E, Ngadjeu CS, et al
Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids
