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Elevated CNS levels of HGF have been measured in patients diagnosed with multiple sclerosis, Parkinsons disease, amyotrophic lateral sclerosis and spinal cord injury [91-94]

The abundance of cysteine residues in proteins increases with organism complexity, ranging from 0.50% in archaea to 2.25% in mammals [38], and is postulated to reflect the evolution of cysteine's signalling and control functions [39,40]

[DOI] [PubMed] [Google Scholar] 170.Murphy M.P., Smith R.A

GDH catalyzed oxidative deamination is the main process for glutamate to enter the TCA cycle in the form of -KG [6]

A notable example is the enzyme that facilitates the conversion of water molecules into oxygen during photosynthesis, which contains four manganese atoms

Thus in the second mechanism, MT can protect the cells from radiation and chemotherapeutic agents by virtue of its free radical scavenging property
