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223 Dynamin-related protein 1 promotes fragmented mitochondrial puncta formation in latent brain metastatic cells, leading to a shift towards fatty acid oxidation (FAO) metabolism that maintains redox homeostasis and survival of tumor cells within the brain microenvironment
As mentioned above, NAC is an oral over-the-counter antioxidant supplement and also is available as an injectable pharmaceutical typically used to protect the liver in cases of acetaminophen overdose
D.MrozkovaP.et al
All human AML cell lines, HL-60 (ACC 3), MOLM-13 (ACC 554), MV4-11(ACC 102), THP-1 (ACC 16), KG-1 (ACC 14), PL-21 (ACC 536) were purchased from DSMZ and validated using STR profiling
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