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Most people in the US consume more than sufficient molybdenum in their diets, making supplementation unnecessary

The accumulation of 4-HNE-protein adducts in tissues reflects the degree of oxidative damage and may provide insight into the progression of the disease [145]

McClure and Massari, 2014

Causes of increased oxidative stress are triggers of hemolytic crisis and include: Fava beans Drugs: antimalarial drugs (e.g., chloroquine, primaquine), sulfa drugs (e.g., trimethoprim-sulfamethoxazole), nitrofurantoin, isoniazid, dapsone, NSAIDs, ciprofloxacin, chloramphenicol Bacterial and viral infections (most common cause): Severe enzymatic deficiency can inhibit respiratory burst activity due to reduced NADPH production in phagocytes

These simulations provide prevalence surfaces against which different traditional and novel strategies for randomisation can be evaluated