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The significance of timing in combination therapy was brought to light by a study conducted by Eastwood et al., which showed that in a model of electrode insertion trauma, sequential delivery of dexamethasone and NAC was more efficacious than simultaneous delivery [4]

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10.1016/j.imlet.2011.04.005 Immunol

Although some studies indicate that ethnic and environmental factors, in addition to genetic factors, can also influence on disease progression, the caution should be exercised in drawing too hasty conclusions

In addition, the glutathione levels in exhaled breath condensate increased after oral steroid treatment compared with pretreatment levels [55]

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