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Description
The Melbourne Women's Midlife Health Project
PMID 22221769
Administration of IV conjugated estrogen (2.5 mg) to postmenopausal women (raising serum estrogen to levels seen in the midluteal phases premenopause) reduced serum insulin concentrations (73)
Abnormal estrogen signaling through ER is a major driver of tumorigenesis in luminal A and luminal B breast cancers [4], as it promotes the proliferation of cancer cells by overexpressing cyclin D1 and c-Myc, both of which enable the tumors to bypass the G1/S checkpoint [5]
The researchers saw similar results with other kinds of cancer
Falkenberg, L
