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The maximum studied cagrilintide dose in combination settings is 4.5 mg weekly

Mounjaro is a glucagon-like peptide-1 (GLP-1) receptor agonist and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist licensed in the UK for treating type 2 diabetes, with weight management indications also approved

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However, when the assay was repeated with 5-amino-6-fluoro-1MQ, an analogue of 5-amino-1MQ that did not interfere with the NAMPT assay, no inhibition of NAMPT was observed with analogue concentrations between 30 and 600 M (data not shown)

M500KCAF0Y, Bio-Rad Laboratories) was used for cytokine profiling
