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Consistent with our findings, PD-L1 regulation by AKT and MEK was also reported in other human tumor cell lines 28,29

Dissociation between dopaminergic response and motor behavior following intrastriatal, but not intravenous, transplant of bone marrow mononuclear stem cells in a mouse model of Parkinsons disease

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More recently, nanocarriers have been engineered to co-deliver therapeutic genes, such as p53, regulatory RNAs (siRNA and miRNA targeting PD-L1, survivin, VEGF, B-cell lymphoma 2 (Bcl-2), and others), and naturally occurring cytolytic peptides, thereby enhancing therapeutic efficacy through gene silencing, apoptosis induction, and immune modulation (Li X