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doi: 10.1002/14651858.cd002086.pub2

While tirzepatide is not primarily eliminated through the kidneys, the gastrointestinal effects of the medication, including potential nausea, vomiting, and diarrhea, could lead to dehydration and electrolyte imbalances that may be particularly problematic in patients with compromised kidney function

A., Hosny, K

Biochem Pharmacol (2019) 159:110

Following the first four weeks, dosages may be raised once weekly by 2.5 mg increments, if tolerated, up to a maximum of 15 mg

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