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We are entirely dependent on dietary intake or supplementation, and even with adequate dietary intake, absorption can be impaired by a range of factors including age-related changes to stomach acid production, certain medications, and digestive conditions

It is important to mentions that IGF-1 receptors are expressed ubiquitously [99]

Growth hormone axis treatments for HIV-associated lipodystrophy: a systematic review

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Urinary or plasma methylmalonic acid (MMA), a substance produced in the body thats dependent on B12, is also helpful for detecting early stages of B12 deficiency