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Curr Phys Med Rehabil Rep (2015) 3:151158 DOI 10.1007/s40141-015-0086-1

Usage Problems: Vitamin B12 Deficiency Despite High Blood Levels If B12 values remain extremely high in a second blood test, the cause can often be difficult to determine, however, is likely related to utilisation problems within the body

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Causes The common cause of vitamin B12 deficiency is malabsorption

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see Table 1) ( While European guidelines recommend up to 4 g/day for adults, most of the included studies administered pharmacological doses ranging from hundreds to thousands of micrograms