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Similarly, we observed increased proliferative capacity of U-1242 MG GBM cells lacking HIF1 following irradiation and enhanced sensitivity to sertraline, especially in combination with irradiation (Figure S9C)

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Compared to ROS induction by treatment with tert-butyl hydroperoxide (TBHP), an exogenous inducer of oxidative stress 37 , ROS levels were only slightly increased in PANC-1 cells and actually decreased MSTO-211H cells (Supplementary Fig