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Astrocyte-neuron interactions in neurological disorders

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Neural regeneration following an injury can be potentially treated with Gly-Pro-Glu (GPE), the amino-terminal peptide of the insulin-like growth factor-1 (IGF-I)
This grade is typically produced for topical applications in skincare products

The mechanism combines the BDNF/NGF surge with suppression of apoptotic cascades and with anti-inflammatory cytokine modulation
