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Xiong, P., Yan, X., Zhu, Q., Qu, G., Shi, J., Liao, C., & Jiang, G

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When opioids are necessary, FDA-approved naltrexone doses ranging from 50 to 100 mg for the treatment of alcohol- and opioid-use disorder often involve a higher dose to overcome antagonism and cautious titration to take effect

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