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To find a more effective method for the cure and treatment of HCC, research for a better understanding of the mechanism involved in the development of cancer, OS-induced damage, and the effects of antioxidants is urgently required (Wang et al., 2016)

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Intriguingly, this mesenchymal resistance was specific to the restriction of methionine/cystine, and not to the depletion of other non-SAA amino acids including leucine (essential), threonine (essential), or glutamine (conditionally essential) (Fig

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Finally, ribosomal hydroxylation by the 2-OGDD protein OGFOD1 is important for translation efficiency since OGFOD1 knockout results in translational stress [89]

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