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Human immunodeficiency virus (HIV) is a major cause of death worldwide

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Glutathione for Vascular and Cellular Brightening: Glutathione reduces oxidative cellular stress around the eye area, shifting melanin synthesis toward the lighter Phaeomelanin pathway and providing antioxidant protection that addresses the oxidative component of both surface pigmentation and the vascular visibility that makes discolouration in this area more pronounced

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Methods A comprehensive literature search was conducted in Scopus, PubMed, and Web of Science for studies published between 1993 and 2023, using a combination of Medical Subject Headings (MeSH) terms and expert-defined keywords