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If you experience common side effects like abdominal cramping or loose stools, talk to your doctor

According to Kannt & Pfenninger in Frontiers in Physiology , NAD is a critical coenzyme in mitochondrial energy metabolism, and strategies that preserve NAD have wide-ranging effects on health and performance (Kannt & Pfenninger, Frontiers in Physiology )

Serious adverse effects appear rare but remain possible until more comprehensive long-term studies are completed

NAD+ Flux Regulation: Studies focus on its mechanism of blocking NNMT, which may otherwise drain methyl groups and Nicotinamide, theoretically boosting the available pool of NAD+

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2002;283:E65866
