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Description
APN is a type II metalloproteinase that belongs to the M1 family (Luan and Xu, 2007)

These encouraging results prompted us to further investigate the in vivo therapeutic potential of these nanomaterials on cataracts

More help This AOP was last modified on November 28, 2025 09:07 Revision dates for related pages Abstract A concise and informative summation of the AOP under development that can stand-alone from the AOP page

The impact of changed redoxin function on ferroptosis could also be based on secondary effects, e.g., the increase in superoxide formation upon loss of mitochondrial redoxins [90,91] or activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway [92,93] , a major regulator of transcription of antioxidant and anti-ferroptotic enzymes [65]
[DOI] [PubMed] [Google Scholar] 20.Amores-Sanchez MI

Miss the timing, and you're chasing diminishing returns
