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UDP-glucuronate serves as a glucuronic acid donor in reactions catalyzed by UDP-glucuronosyltransferase (EC 2.4.1.17)

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We have identified a strategy to enhance the efficacy of CDK4/6 and ER inhibition and extend the potential role of promoting ferroptosis as an anti-cancer strategy in ER+ and potentially TN breast cancers

2023;8(12):e170671

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It has been shown that cisplatin can deplete intracellular glutathione that leads to glutathione peroxidases (GPX) inhibition and induce ferroptosis [64]