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Type 1 IFNs can be induced following the activation of endosomal TLR7 and TLR9, or cytosolic cGAS-STING (cyclic GMP-AMP synthase-stimulator of interferon genes), by host, viral, or bacterial DNA
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Book review: GABA and glutamate in the human brain
L.BeckwithR

The reversal of lipid peroxidation by diosgenin is also worthy of notable mention [150, 151]

and this appears to be a result of the disease itself, not of decreased dietary intake of vitamin C (Sinclair 1994)