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Among all the poses from IFD, docked GSSG on C23 represents many polar contacts with several nearby residues on GLRX protein including hydrogen bonding with C83, N55, Y25, G82, P24, T22, and K20 which stabilizes the complex significantly

The actions of some drugs as substrates or inhibitors of enzymes involved in xenobiotic metabolism are a common reason for hazardous drug interactions

Biochemistry, pathophysiology, and regulation of linear ubiquitination: intricate regulation by coordinated functions of the associated ligase and deubiquitinase

Ho ET, Trookman NS, Sperber BR, et al

& Cerami Anthony, P

These mechanisms not only disrupt neuronal integrity but also contribute to persistent cognitive and behavioral deficits